Monodisperse microspheres

Emulsification is often an intermediate process step in the fabrication of microspheres. Typically a polymer solution is emulsified, followed by removal of the solvent by means of evaporation. In other cases monomers are emulsified followed by a thermal or UV polymerization step or a polymer melt is emulsified and successively cooled down to solidify the droplets. The fabricated microspheres are usually collected by means of filtering or centrifuging the resulting dispersion. For many applications microspheres need to have a monodisperse size distribution.

The Nanomi technology is especially suited for the production of monodisperse microspheres. The membranes are chemically resistant to all solvents and can withstand very high process temperatures. Furthermore the process yields monodisperse droplet size distributions and thus monodisperse microsphere distributions.

Our main focus in monodisperse microsphere fabrication is the production of advanced drug delivery systems for sustained release.